臨床研究等提出・公開システム

Evaluation of the efficacy of mineral trioxide aggregate cement sealing to a root canal with apical destruction.

Study of the efficacy of root sealing with MTA cement

Saito Noriko

Hiroshima University Hospital

1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553, Japan

r14saito@hiroshima-u.ac.jp

Saito Noriko

Hiroshima University Hospital

1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553, Japan

+81-82-257-5656

r14saito@hiroshima-u.ac.jp

Recruiting

Feb. 28, 2023

Interventional

single arm study

open(masking not used)

uncontrolled control

single assignment

treatment purpose

1. Ages 18 old over or older with written informed consent from the individual
2. Outpatients who can come in for treatment and follow-up
3. Patients with a single root and a single root canal with a radiographic transparency of the root apex before treatment and an enlarged root apex of 0.55 to 0.80 mm

1. patients with severe clenching and bruxism
2. patients with root fractures
3. patients with periodontal-endodontic lesions and endodontic-periodontal lesions 4. patients with perforations
4. patients with perforations
5. patients with a history of hypersensitivity, such as rash or dermatitis, to chemical substances, including raw materials of the materials under study
6. patients who are participating or intend to participate in other clinical research studies during the course of participation in this study
Patients who are deemed to interfere with, limit, or confound the evaluation specific to the clinical research protocol. 8.
8. a principal investigator or employee of the institution directly involved in this or other clinical research, or a family member of such an employee, principal investigator, etc.
9. patients with findings of suspected root cysts or root granulomas in the subject tooth
10. patients who are or may be pregnant
11. patients whose clinical symptoms (spontaneous pain, bruxism, gingival redness and swelling, fistula) do not resolve after several standard root canal procedures

Both

apical periodontitis

Seal the root canal up to 3-5 mm from the apex with MTA cement.

apical periodontitis

MTA cement

Percentage of patients with reduced or eliminated root tip bone defect volume calculated from dental CBCT images

Evaluation of periapical tissue healing tendency using dental radiographs based on the PAI score

+81-82-257-1551

Feb. 17, 2023

No

none