臨床研究等提出・公開システム

Scientific Title	Study to Investigate the GLP-1 Secretion-Promoting Effect of Foods Containing Allulose
Public Title	Study to Investigate the GLP-1 Secretion-Promoting Effect of Foods Containing Allulose

Contact for Scientific Queries	Name	Kawashima Sachiko
	Affiliation	Kyoto University Hospital
	Address	54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto
	Telephone	+81-75-751-3560
	E-mail	skawashi@kuhp.kyoto-u.ac.jp
Contact for Public Queries	Name	Ikeda Kaori
	Affiliation	Kyoto University Hospital
	Address	54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto
	Telephone	+81-75-751-4639
	E-mail	krikeda@kuhp.kyoto-u.ac.jp

Recruitment status	Recruiting

Anticipated date of first enrollment		Mar. 26, 2025
Actual date of first enrollment		July. 02, 2025
Target sample size		20
Study Type		Interventional
Study Design	allocation	randomized controlled trial
	masking	double blind
	control	active control
	assignment	crossover assignment
	purpose	prevention purpose
Key inclusion & exclusion criteria	Inclusion Criteria	Healthy adult
	Exclusion Criteria	Individuals with impaired glucose tolerance (as it may affect test results related to blood glucose, etc.). Individuals with a history of using incretin-related drugs (as it may affect test results related to blood glucose, etc.). Individuals with a BMI below 18.5 or above 30.0. Individuals who are pregnant or plan to give birth during the study period. Other individuals deemed unsuitable by the principal investigator.
	Age Minimum	20age old over
	Age Maximum	No limit
	Gender	Both
Health Condition(s) or Problem(s) Studied		Diabetes Mellitus
Intervention(s)		Administration of 10 g of allulose; Administration of 10 g of sucrose
Health Condition(s) Keyword
Intervention(s) Keyword
Health Condition(s) Code		D003920
Intervention(s) Code
Primary Outcome(s)		Change in blood GLP-1 concentration
Secondary Outcome(s)		Change in blood GIP concentration Change in plasma glucose levels Change in serum insulin concentration Change in sensation of hunger

Primary Sponsor

Source of Monetary Support / Secondary Sponsor	UHA Mikakuto Co.,Ltd.
Secondary Sponsor

Source of Monetary Support
Secondary Sponsor

Name of Certified Review Board	Kyoto University Certified Review Board
Address	Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, JAPAN, Kyoto
Telephone	+81-75-753-4680
E-Mail	ethcom@kuhp.kyoto-u.ac.jp
Approval Status	Approval
Date of approval	Mar. 17, 2025

Secondary ID(s)
Issuing Authority

Countries of Recruitment（Except Japan）	none

History of Changes

List of change history