臨床研究等提出・公開システム

Postoperative analgesic effect of indwelling PENG block catheter

Analgesic effect of indwelling PENG block

NAKAZAWA KEISUKE

Nihon University School of Medicine Itabashi Hospital

Tokyo Itabashi-ku Kamimachi 30-1

nakazawa.keisuke@nihon-u.ac.jp

Nakazawa Keisuke

Nihon University School of Medicine Itabashi Hospital

Tokyo Itabashi-ku Kamimachi 30-1

+81-339728111

nakazawa.keisuke@nihon-u.ac.jp

Not Recruiting

July. 24, 2024

Interventional

randomized controlled trial

open(masking not used)

no treatment control/standard of care control

single assignment

treatment purpose

1) Adults 20 years of age or older
2) Patients with BMI between 18.5 and 25.0 kg/m2
3) Patients with American Society of Anesthesiologists Preanesthetic Risk Assessment (ASA-PS)3 or less (ASA-PS Classification 1: No organic, biochemical, or psychiatric abnormalities. Classification 2: Mild to moderate systematic disorder. Classification 3: Severe systematic disorder. Classification 4: Severe systemic disorders that are life-threatening and cannot be cured by surgery. Classification 5: Dying.)
4) Persons who give written consent to participate in the research.

1) Patients who do not meet the above selection criteria
2) Patients allergic to amide-type local anesthetics
3) Patients on anticoagulation therapy with PT-INR (Prothrombin Time International Normalized Ratio) >1.2 or on dual anti-platelet therapy (DAPT: Dual Anti-platelet therapy).(DAPT: Dual Anti-platelet therapy), excluding biazpirin monotherapy and prophylactic low molecular weight heparin therapy.DAPT (Dual Anti-platelet Therapy), excluding biazpirin monotherapy and prophylactic low molecular weight heparin therapy
4) Patients with any of the contraindications listed in the package insert.
5) Patients with moderate to severe hepatic dysfunction
6) Patients with arrhythmia requiring pacemaker insertion 7) Patients who meet all of the "selection criteria" and none of the "exclusion criteria" among the above-mentioned eligible patients.
7) Patients who meet all of the above selection criteria and none of the exclusion criteria.
8) Patients who have refused to participate in this study.

Femoral neck fractures, idiopathic femoral head necrosis, osteoarthritis of the hip

To compare the clinical efficacy of PENG block and continuous catheter analgesia after orthopedic hip surgery versus a single PENG block group.

Pain score (VAS scale: Visual Analogue Scale or NRS: Numerical rating scale) at 0, 2, 6, 12 (before sleep and after waking), 24, and 24 hours after surgery.

Number of cases requiring additional rescue analgesia (NSAIDs, weak opioid analgesics) prescribed on the ward postoperatively and the time since surgery for which the additional analgesia was requested; presence of PONV (postoperative nausea and vomiting); vital signs (max/min/average blood pressure, respiratory rate, pulse rate) upon leaving the operating room; degree of muscle weakness by manual leg muscle strength degree of muscle weakness by lower leg manual muscle strength test. Time (in days) to rehabilitation ambulation. Number of days in hospital. Presence or absence of postoperative delirium. Presence or absence of sleep disturbance.

+81-3-3972-8111

Oct. 06, 2023

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