臨床研究等提出・公開システム

Scientific Title	An exploratory clinical study on the relaxation effects of a single session of alpha-theta training in patients hospitalized in a palliative care unit.
Public Title	An exploratory clinical study on the relaxation effects of a single session of alpha-theta training in patients hospitalized in a palliative care unit.

Contact for Scientific Queries	Name	Miura Tomofumi
	Affiliation	National Center Hospital East
	Address	Kashiwanoha 6-5-1, Kashiwa, Chiba
	Telephone	+81-4-7134-6977
	E-mail	tomiura@east.ncc.go.jp
Contact for Public Queries	Name	Miura Tomofumi
	Affiliation	National Cancer Center Hospital East
	Address	Kashiwanoha 6-5-1, Kashiwa, Chiba
	Telephone	+81-4-7134-6977
	E-mail	tomiura@east.ncc.go.jp

Recruitment status	Pending

Anticipated date of first enrollment		April. 13, 2026
Target sample size		20
Study Type		Observational
Study Design	allocation	single arm study
	masking	open(masking not used)
	control	uncontrolled control
	assignment	single assignment
	purpose	health services research
Key inclusion & exclusion criteria	Inclusion Criteria	1) be 18 years or more 2) be diagnosed as cancer 3) be admitted in palliative care unit 4) be able to perform EEG and ECG test 5) keep sitting or lying about 30 minutes 6) be a Japanease native speaker 7) be negative for confusion assessment method 8) be able to understand and sign in ICF
	Exclusion Criteria	1) be diagnosed as brain tumor, brain metastasis and leptomeningeal metastasis 2) have severe physical or psychological sympotoms 3) be diagnosed as bipolar disorders or personality disorder 4) under treatment of CBT or mindfullness 5) hearing loss requiring hearing aids 6) restricted tongue and jaw mobility 7) be judged as unsuitable for participatin by physicians
	Age Minimum	18age old over
	Age Maximum	No limit
	Gender	Both
Health Condition(s) or Problem(s) Studied		cancer
Intervention(s)		to perform alpha-theta training for 30 minutes
Health Condition(s) Keyword		cancer
Intervention(s) Keyword		alpha-theta training, neurofeedback
Health Condition(s) Code		D009369
Intervention(s) Code		D058765
Primary Outcome(s)		the change of the Healing Scale
Secondary Outcome(s)		the change of mood and symptoms the change of EEG and ECG

Source of Monetary Support	KAKENHI

Name of Certified Review Board	the institutional review board of the National Cancer Center, Japan
Address	Kashiwanoha 6-5-1, Kashiwa, Chiba, Chiba
Telephone	+81-4-7133-1111
E-Mail	mikouhyou@mikouhyou
Approval Status	Approval
Date of approval	Mar. 19, 2026

Plan to share IPD	No

Countries of Recruitment（Except Japan）	None