臨床研究等提出・公開システム

Date of registration	Oct. 02, 2024
Last modified on	Oct. 02, 2024
Trial ID	jRCT1030240368

Scientific Title	Study on the correlation between NAD-related metabolites and various measurement items related to physiological aging in a high-dose nicotinamide mononucleotide (NMN) study
Public Title	The correlation between NAD-related metabolites and items related to physiological aging in a high-dose nicotinamide mononucleotide (NMN) study

Contact for Scientific Queries	Name	Igarashi Masaki
	Affiliation	The University of Tokyo Hospital
	Address	7-3-1 Hongo, Bunkyo-ku, Tokyo
	Telephone	+81-338155411
	E-mail	igarashi-tky@umin.ac.jp
Contact for Public Queries	Name	Takaoka Yuriko
	Affiliation	The University of Tokyo Hospital
	Address	7-3-1 Hongo, Bunkyo-ku, Tokyo
	Telephone	+81-338155411
	E-mail	johntakaoka223@gmail.com

Recruitment status	Not Recruiting

Study Design
Anticipated date of first enrollment		May. 24, 2024
Actual date of first enrollment		May. 24, 2024
Target sample size		62
Study Type		Observational



	purpose	prevention purpose
Key inclusion & exclusion criteria	Inclusion Criteria	There will be no new subjects recruited due to the secondary use of data.
	Exclusion Criteria	There will be no new subjects recruited due to the secondary use of data.
	Age Minimum	No limit
	Age Maximum	No limit

Health Condition(s) or Problem(s) Studied		Older adults who do not take medicine Improvements are expected in various measurement items related
Health Condition(s) Keyword		older adults
Health Condition(s) Code		D000368
Primary Outcome(s)		Between-group comparison of NAD-related metabolites (NAD, NMN, nicotinamide, NA, NR, NAR, NAMN, NAAD) Between-group comparison of body composition (BIA method) and skin analysis Correlation between NAD-related metabolites (NAD, NMN, nicotinamide, NA, NR, NAR, NAMN, NAAD) and various measurement items related to physiological aging in a high-dose NMN study Correlation between the already measured NAD blood concentration in a high-dose NMN study and body composition (BIA method) and skin analysis

Primary Sponsor	MIRAILAB BIOSCIENCE Inc in a high-dose NMN study

Secondary Sponsor	Not applicable

Source of Monetary Support	MIRAILAB BIOSCIENCE Inc
Secondary Sponsor	Not applicable

Name of Certified Review Board	The University of Tokyo, Clinical Research Review Board
Address	7-3-1 Hongo, Bunkyo-ku, Tokyo, Tokyo
Telephone	+81-3-5841-3600
E-Mail	mgr-ohrs@m.u-tokyo.ac.jp
Approval Status	Approval
Date of approval	May. 27, 2024

Plan to share IPD	No

Countries of Recruitment（Except Japan）	none