臨床研究等提出・公開システム

Date of registration	Aug. 08, 2022
Last modified on	Jan. 26, 2026
Trial ID	jRCTs041220049

Scientific Title	Effects of royal jelly on cognitive function in postmenopausal women
Public Title	Royal jelly and cognitive function

Contact for Scientific Queries	Name	Matsushita Hiroshi
	Affiliation	Aichi Medical University Hospital
	Address	1-1 Yazako-karimata, Nagakute, Aichi 480-1195, Japan
	Telephone	+81-561-62-3311
	E-mail	hirosm@aichi-med-u.ac.jp
Contact for Public Queries	Name	Matsushita Hiroshi
	Affiliation	Aichi Medical University School of Medicine
	Address	1-1 Yazako-karimata, Nagakute, Aichi 480-1195, Japan
	Telephone	+81-561-62-3311
	E-mail	hirosm@aichi-med-u.ac.jp

Recruitment status	Recruiting

Anticipated date of first enrollment		Aug. 08, 2022
Target sample size		80
Study Type		Interventional
Study Design	allocation	randomized controlled trial
	masking	double blind
	control	placebo control
	assignment	parallel assignment
	purpose	basic science
Key inclusion & exclusion criteria	Inclusion Criteria	Postmenopausal women, aged 45-65 years, complaining of subjective forgetfulness
	Exclusion Criteria	1. Allergic to royal jelly, bee products, or milk 2. Asthma 3. Mini-Mental State Examination (MMSE) less tha n 23 4. Women who have any medical complications, o r take drugs that affect cognitive function
	Age Minimum	45age old over
	Age Maximum	65age old not
	Gender	Female
Health Condition(s) or Problem(s) Studied		subjective forgetfulness
Intervention(s)		Women in the royal jelly and placebo groups take capsules containing dried royal jelly (equivalent to 3000 mg of fresh royal jelly) or placebo, respectiv ely, daily for 6 months
Health Condition(s) Keyword		subjective forgetfulness
Primary Outcome(s)		Cognitive function [CNS Vital Signs (Cognitrax)]
Secondary Outcome(s)		1. Mini-Mental State Examination (MMSE) 2. Serum amyloid beta

Source of Monetary Support / Secondary Sponsor	Japan Royal Jelly Fair Trade Council

Name of Certified Review Board	Certified Clinical Research Review Board of Aichi Medical University Hospital
Address	1-1 Yazako-karimata, Nagakute, Aichi 480-1195, Japan, Aichi
Telephone	+81-561-62-3311
E-Mail	amu_crb@aichi-med-u.ac.jp
Approval Status	Approval
Date of approval	July. 19, 2022

Plan to share IPD	No

Countries of Recruitment（Except Japan）	none

History of Changes

No	Publication date
2	Jan. 26, 2026	(this page)	Changes
1	Aug. 08, 2022	Detail

List of change history