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May. 13, 2026

May. 13, 2026

jRCT1051260047

Research on chronic pain treatment with human-derived mesenchymal stem cell conditioned medium

Research on chronic pain treatment with MSC-CM

Tachibana Jun

Stem Cell Clinic Tokyo

5-9-15 Ginza, Chuo-ku, Ginza Seigetsudo Building 5F

+81-362806020

kansaibou.clinic.tokyo@gmail.com

Tachibana Jun

Stem Cell Clinic Tokyo

5-9-15 Ginza, Chuo-ku, Ginza Seigetsudo Building 5F

+81-362806020

kansaibou.clinic.tokyo@gmail.com

Recruiting

Mar. 25, 2026

100

Observational

single arm study

open(masking not used)

historical control

single assignment

treatment purpose

1. Individuals who did not experience satisfactory pain relief effects with standard therapy.
2. Individuals who do not wish to undergo treatment with drugs commonly used in standard therapy due to concerns about side effects, and whose physicians have determined that treatment with conditioned medium is appropriate for chronic pain relief.
<Eligibility Criteria>
Patients meeting the following criteria are eligible:
1. Individuals aged 18 years or older.
2. Individuals with normal capacity to consent.
3. Individuals who have been provided with the informed consent document for this treatment, have received sufficient explanation, and are capable of providing written consent freely and voluntarily.
4. Individuals for whom the attending physician has recognized the necessity of treatment.

<Exclusion Criteria>
Individuals meeting any of the following conditions will be excluded:
1. Users of narcotics or stimulants.
2. Individuals deemed inappropriate by the attending physician.

18age old over
No limit

Both

chronic pain

Arthritis pain, Back pain, Persistent pain, Neuropathic pain, Musculoskeletal pain

D009132

The self-reported symptoms of pain in the research subjects are as follows:
1) Impact of pain on daily life
2) Pattern of pain
3) Intensity of pain (Numerical Rating Scale; NRS)
4) Location of pain
5) Characteristic of pain

Stem Cell Clinic Tokyo
Safety Assessment and Clinical Research in Japan
13-16 Sanjo Minamicho, Ashiya City, Hyogo

+81-797-22-5511

info.rinrishinsa@gmail.com
Approval

Mar. 25, 2026

No

none