臨床研究等提出・公開システム

Scientific Title	Investigate the neural subsrtate underlyng the effect of rTMS on memory improvements (N/A)
Public Title	N/A (N/A)

Contact for Scientific Queries	Name	Abe Mitsunari
	Affiliation	National Center of Neurology and Psychiatry
	Address	Ogawahigashi 4-1-1, Kodaira, Tokyo
	Telephone	+81-423462206
	E-mail	mitsunari.abe.a8@ncnp.go.jp
Contact for Public Queries	Name	Tanaka Shinya
	Affiliation	National Center of Neurology and Psychiatry
	Address	Ogawahigashi 4-1-1, Kodaira, Tokyo
	Telephone	+81-423412712
	E-mail	mitsunari.abe.a8@ncnp.go.jp

Recruitment status	Recruiting

Anticipated date of first enrollment		June. 25, 2023
Actual date of first enrollment
Target sample size		70
Study Type		Observational
Study Design	allocation	single arm study
	masking	open(masking not used)
	control	no treatment control/standard of care control
	assignment	single assignment
	purpose	basic science
Key inclusion & exclusion criteria	Inclusion Criteria	Age 20-40 or 60-75 The patients who has no past history of head surgery, neurological or psychiatric disorders, epileptic seizures. The patients who has no medication of drug that may affect brain functions
	Exclusion Criteria	The patients who had past history of head surgery, neurological or psychiatric disorders, epileptic seizures. The patients who had medication of drug that may affect brain functions
	Age Minimum	No limit
	Age Maximum	No limit
	Gender
Health Condition(s) or Problem(s) Studied		Healthy volunteers
Intervention(s)
Health Condition(s) Keyword
Intervention(s) Keyword
Health Condition(s) Code
Intervention(s) Code
Primary Outcome(s)		Examing higher activity in the hippocampus, and greater functional connectivity between the hippocampus and the cortex after rTMS
Secondary Outcome(s)		Examining the relationship between the chnage in activity in the hippocampus and perfromance of memroy tasks

Primary Sponsor	N/A

Source of Monetary Support / Secondary Sponsor
Secondary Sponsor

Source of Monetary Support
Secondary Sponsor

Name of Certified Review Board	Ethics Committee of NCNP
Address	Ogawahigashi 4-1-1, Kodaira, Tokyo , Tokyo
Telephone	+81-423462206
E-Mail	rinri-jimu@ncnp.go.jp
Approval Status	Approval
Date of approval

Plan to share IPD	No
Plan description

Secondary ID(s)
Issuing Authority

Countries of Recruitment（Except Japan）	N A

History of Changes

No	Publication date
2	July. 09, 2025	(this page)	Changes
1	June. 25, 2023	Detail

List of change history